Status:

UNKNOWN

Faecal Microbiota Transplantation for Microscopic Colitis

Lead Sponsor:

Hvidovre University Hospital

Conditions:

Microscopic Colitis

Eligibility:

All Genders

18+ years

Phase:

EARLY_PHASE1

Brief Summary

A pilot study investigating if orally administrated faecal microbiota transplantation capsules have the potential to treat active microscopic colitis.

Eligibility Criteria

Inclusion

  • Diagnosis of microscopic colitis
  • Date of diagnosis/histological confirmation \< 12 months
  • Active disease according to Hjortswang's criteria

Exclusion

  • Diagnosed with ulcerative colitis or Crohn's disease
  • Diagnosed with celiac disease
  • Active gastrointestinal infection
  • Previous bowel resection of bowel (except appendectomy)
  • Previous cholecystectomy
  • Treatment with systemic steroid within 4 weeks, including budesonide
  • Antibiotics 3 months prior
  • Severe immunodeficiency,
  • Pregnancy, planned pregnancy and breastfeeding
  • Treatment with constipants such as psyllium, loperamide, bile binders, opium drops or codeine up to 2 weeks before inclusion and during participation

Key Trial Info

Start Date :

September 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2025

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05998174

Start Date

September 1 2023

End Date

March 1 2025

Last Update

August 18 2023

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