Status:
UNKNOWN
The Impact of Coagulation Disorders on the Diagnosis and Prognosis of Sepsis
Lead Sponsor:
Ruijin Hospital
Conditions:
Sepsis
Coagulation Disorder
Eligibility:
All Genders
18-90 years
Brief Summary
The study was a retrospective, single-center clinical study. From all patients admitted to the emergency ICU during the period of 2013.1.1-2019.12.31, the investigators screened all patients who met t...
Eligibility Criteria
Inclusion
- Time from clinical symptoms to admission ≤ 7 days；
- infection was diagnosed by clinician
- Systemic inflammatory response syndrome，Systemic inflammatory response syndrome was defined as the presence of 2 or more of the following: (1) temperature \<36℃or \>38℃, (2) heart rate \>90 beats per minute, (3) respiratory rate \>20 breaths per minute or PaCO2 \< 32 mm Hg, or (4) white blood cell count ≥12 000 cells/mm3 or≤4000 cells/mm
Exclusion
- Pregnancy and lactation
- Have hematological diseases (including acute and chronic leukemia, hemolytic anemia, hemophilia, aplastic anemia, bone marrow fibrosis, congenital or acquired coagulation factor deficiency, etc.)
- Anticoagulant or antiplatelet drug treatment
- 24 hours after severe trauma or surgery
- Autoimmune diseases
- cirrhosis
- Malignant tumor patients with personal history or undergoing radiotherapy, chemotherapy and targeted treatment
Key Trial Info
Start Date :
June 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
552 Patients enrolled
Trial Details
Trial ID
NCT05998733
Start Date
June 1 2022
End Date
June 1 2024
Last Update
August 21 2023
Active Locations (1)
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1
Department of Emergency, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China, 200025