Status:

UNKNOWN

Elevated Initial APRI Value Was Associated With SALD

Lead Sponsor:

Chinese Medical Association

Conditions:

Liver Dysfunction

Sepsis-associated Liver Dysfunction

Eligibility:

All Genders

18-90 years

Brief Summary

Sepsis, characterized by severe organ dysfunction related to a dysregulated immune response to infection, is often life-threatening in clinical settings. Sepsis can progress to multiple organ dysfunct...

Detailed Description

We included adult sepsis patients (≥18 years) as study participants, but only those who had data available for their first hospitalization and first ICU admission were enrolled in our study, if they h...

Eligibility Criteria

Inclusion

  • adult sepsis patients (≥18 years)

Exclusion

  • all types of chronic liver disease;
  • viral hepatitis;
  • primary acute cholangiopathies;
  • cholecystitis;
  • hepatic infarction;
  • liver necrosis;
  • liver trauma;
  • length of ICU stay \< 24 hours;
  • Patients without simultaneous AST and PLT data in the first 24 hours after ICU admission.

Key Trial Info

Start Date :

January 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2023

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT05999331

Start Date

January 1 2019

End Date

September 30 2023

Last Update

August 21 2023

Active Locations (1)

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1

Institute of General Surgery of Jinling Hospital

Nanjing, Jiangsu, China, 210002