Status:

RECRUITING

Prehabilitation for Colorectal Cancer Patients With Low Functional Capacity and Malnutrition

Lead Sponsor:

McGill University

Collaborating Sponsors:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Conditions:

Prehabilitation

Malnutrition

Eligibility:

All Genders

65+ years

Phase:

NA

Brief Summary

Despite multi-modal prehabilitation (nutrition, exercise, and psychosocial interventions), 60% of older elective colorectal cancer surgery patients with poor physical function were unable to reach a m...

Detailed Description

The investigators propose a randomized controlled trial of nutrition prehabilitation alone vs nutrition prehabilitation with supportive exercise in patients with malnutrition and 6MWD \<400m before el...

Eligibility Criteria

Inclusion

  • Patients aged 65 years and older;
  • Patients with cancer scheduled for primary colorectal resection;
  • Patients with 6MWD at baseline less than 400 m;
  • Patients with Patient-Generated Subjective-Global Assessment (malnutrition assessment) score equal or greater than 9.

Exclusion

  • Patients with history of premorbid conditions that contraindicate exercise including dementia, -Parkinson's disease or previous stroke with paresis;
  • Metastatic cancer;
  • Patients who do not speak English or French and cannot be accompanied by someone who speaks English or French;

Key Trial Info

Start Date :

January 31 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05999370

Start Date

January 31 2022

End Date

December 1 2026

Last Update

May 9 2025

Active Locations (1)

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1

MUHC Research Ethics Board

Montreal, Quebec, Canada, H4A 3T2