Status:
COMPLETED
Comparison of Optical Coherence Tomography Angiography Microvascular Changes in Primary Open Angle and Primary Angle Closure Glaucoma
Lead Sponsor:
Omar Said
Conditions:
Glaucoma,Primary Open-Angle ,Primary Angle Closure
Eligibility:
All Genders
18+ years
Brief Summary
This work aims to study the peripapillary and macular microvascular changes in primary open angle and primary angle closure glaucoma using Optical Coherence Tomography Angiography (OCTA).
Detailed Description
After approval of the local institutional ethics committee and local institutional review board, all patients presenting to the outpatient clinic of the department of Ophthalmology in the universities...
Eligibility Criteria
Inclusion
- Age ≥ 18 years old.
- Fulfilling Diagnostic criteria of PACG patients :occluded angle by gonioscopy in which \> 180˚ of trabecular meshwork cannot be seen , IOP\>21, Optic disc and RNFL damage due to glaucoma
- Diagnosed POAG patient: open anterior chamber angle ,IOP\>21 ,Optic disc and RNFL damage due to glaucoma
- Healthy patient: normal anterior chamber, open angle and normal fundus.
Exclusion
- History of other causes of optic neuropathy.
- History of systemic diseases. (HTN, DM, Cardiac).
- Previous ocular surgeries or Laser iridotomy.
- Poor quality of OCTA image less than 4/10.
- Refractive errors \> 6 diopters sphere, \>3 diopter cylinder
- Poor cooperation or fixation with the OCTA examination.
- Secondary causes of glaucoma
- Media opacity that interfere with quality of image (dense cataract,corneal opacity,…)
- Previous acute attack of ACG
Key Trial Info
Start Date :
April 5 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 20 2023
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06000176
Start Date
April 5 2022
End Date
July 20 2023
Last Update
August 21 2023
Active Locations (1)
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1
Athar Mohamed Mohamed Makhlouf
Al Fayyum, Egypt