Status:
RECRUITING
Enhancing Memory in CPT for PTSD
Lead Sponsor:
VA Office of Research and Development
Conditions:
Stress Disorders, Post-Traumatic
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Several psychotherapies for posttraumatic stress disorder (PTSD) have a strong evidence base for their efficacy, but nonresponse rates are high, particularly among older Veterans. Accumulating evidenc...
Detailed Description
Posttraumatic stress disorder (PTSD) is prevalent among Veterans and is a substantial public health burden. Several psychotherapies, including cognitive processing therapy (CPT), have a strong evidenc...
Eligibility Criteria
Inclusion
- Veterans with DSM-5 diagnoses of PTSD via the Clinician Administered PTSD Scale (CAPS-5)
- Age \>59
Exclusion
- daily benzodiazepine use (due to memory impairing effects)
- bipolar or psychotic disorders
- current suicidal ideation with plan or intent
- current moderate or severe substance use disorder not in remission for \>1 mo.
- severe traumatic brain injury
- a Montreal Cognitive Assessment (MoCA) indicative of dementia
- or other disorders that would severely limit study participation
Key Trial Info
Start Date :
October 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06000475
Start Date
October 15 2024
End Date
June 30 2026
Last Update
October 14 2025
Active Locations (1)
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1
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA
Philadelphia, Pennsylvania, United States, 19104-4551