Status:
UNKNOWN
Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections
Lead Sponsor:
University of Manitoba
Conditions:
Osteoarthritis, Knee
Chronic Knee Pain
Eligibility:
All Genders
40-80 years
Phase:
PHASE4
Brief Summary
Genicular nerve neurolysis (GN) constitutes a relatively novel technique, whereby different chemical compounds (i.e. alcohol, phenol) are injected in close proximity to the genicular nerves of the kne...
Detailed Description
This study will allow us to determine if ultrasound-guided phenol genicular neurolys is superior to intra-articular steroid injection in terms of analgesia and functional outcomes, providing a more ef...
Eligibility Criteria
Inclusion
- Severe knee pain for more than 6 months, defined as Numeric rating scale (NRS) score of 6 and greater, unresponsive to conservative medical treatment
- Radiological OA grade 2 to 4 (Kellgren-Lawrence scale)
Exclusion
- Previous total knee replacement on the index knee
- Prior knee radiofrequency ablation on the index knee
- Connective tissue diseases with knee involvement (e.g. rheumatoid arthritis)
- Body mass index ≥ 40 kg/m2
- Uncontrolled coagulopathy, defined as supratherapeutic dose of anticoagulation medication
- Allergy to local anesthetics
- Unstable opioid consumption, defined as an increase \>10% in dosage during the last 3 months prior to recruitment.
Key Trial Info
Start Date :
October 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06000709
Start Date
October 20 2023
End Date
July 31 2024
Last Update
October 10 2023
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