Status:

RECRUITING

Predictive Value of Soluble CD146 in Glioblastoma Patients

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Conditions:

Glioblastoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Glioblastoma is the most common malignant primary brain tumor with poor prognosis because of its diffusive and infiltrative nature. The FDA approved the use of the anti-VEGF antibody bevacizumab in re...

Eligibility Criteria

Inclusion

  • \- Adult patients with recurrent IDHwt glioblastoma
  • Relapse after standard first line treatment (radio-chemotherapy)
  • Candidate for bevacizumab treatment
  • Able to be monitored by MRI
  • KPS ≥ 60%
  • Written signed consent form

Exclusion

  • Pregnancy or breast feeding
  • Life expectancy less than 3 months
  • Bevacizumab in first line treatment
  • Other concomitant life-threatening disease
  • Under legal protection

Key Trial Info

Start Date :

January 30 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

55 Patients enrolled

Trial Details

Trial ID

NCT06001281

Start Date

January 30 2024

End Date

December 1 2026

Last Update

February 2 2024

Active Locations (1)

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1

Service de Neuro-oncologie

Marseille, France, 13005