Status:

RECRUITING

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

Lead Sponsor:

Icahn School of Medicine at Mount Sinai

Collaborating Sponsors:

Aalborg University

Conditions:

Crohns Disease

Pregnancy

Eligibility:

All Genders

18+ years

Brief Summary

The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bo...

Detailed Description

Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a chronic, progressive inflammatory disease of the intestinal tract. The etiology of IBD is not well un...

Eligibility Criteria

Inclusion

  • The ability to sign and date an informed consent form
  • Be pregnant, or wishing to become pregnant in the near future and enroll the infant that the individual is pregnant with
  • Aged 18 or older
  • English-speaking (this observational study uses non-validated questionnaires that are only available in English)
  • Of any ethnicity
  • Be a spouse, related household member (sibling, parent, etc.) or a child of an enrolled pregnant person

Exclusion

  • Individuals who are unable to give informed consent
  • Be diagnosed with a pregnancy complication, such as intrauterine fetal demise/stillbirth, preeclampsia, hyperemesis gravidarum, or have an active infection, including chorioamnionitis or sepsis.

Key Trial Info

Start Date :

August 15 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 31 2027

Estimated Enrollment :

46 Patients enrolled

Trial Details

Trial ID

NCT06001450

Start Date

August 15 2023

End Date

August 31 2027

Last Update

January 7 2026

Active Locations (1)

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Icahn School of Medicine at Mount Sinai

New York, New York, United States, 10128