Status:
NOT_YET_RECRUITING
Right Ventricular Dysfunction in Chronic Heart Failure
Lead Sponsor:
University of Siena
Collaborating Sponsors:
Italian Society of Cardiology
Conditions:
Chronic Heart Failure
Right Ventricular Dysfunction
Eligibility:
All Genders
18-90 years
Brief Summary
The goal of this multi center observational prospective study is to analyze the concordance between the signs and symptoms of RHF and echocardiographic features of RVD in patient with heart failure. T...
Detailed Description
Right ventricular dysfunction (RVD) and pulmonary hypertension (PH) have been recognized as two important prognostic features in patients with left side heart failure (HF). Nevertheless literature doe...
Eligibility Criteria
Inclusion
- All patients with a diagnosis of chronic heart failure made according to the recommendations of the ESC guidelines through the simultaneous presence of signs and symptoms of disease associated with BNP and NT proBNP levels \> 100 and 300 pg/ml respectively which are associated with a modest increase PAPS \> 30 mmHg with or without right ventricular dilatation.
Exclusion
- Patients with dyspnea of non-cardiogenic origin, related to systemic respiratory diseases, pulmonary embolism, patients with primary pulmonary hypertension will be excluded.
- Patients with heart failure linked to primary valvular pathologies or infiltrative pathologies, secondary and on a genetic basis, patients diagnosed with acute heart failure in non-optimized therapy for at least 3 months will also be excluded. - Patients with systemic inflammatory neoplastic diseases, advanced liver and kidney diseases awaiting transplantation will be excluded.
Key Trial Info
Start Date :
September 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT06002321
Start Date
September 1 2023
End Date
September 1 2026
Last Update
August 21 2023
Active Locations (14)
Enter a location and click search to find clinical trials sorted by distance.
1
Centro Cardiologico Monzino
Milan, Milano, Italy, 20138
2
Department of Medicine, Surgery and Dentistry, Università di Salerno
Fisciano, Salerno, Italy, 84084
3
SC Universitaria di Cardiologia - UTIC Policlinico Riuniti Foggia
Foggia, Italy, 71121
4
Department of Clinical and Experimental Medicine, Operativee Unit of Cardiology, University of Messina
Messina, Italy, 98125