Status:

RECRUITING

Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

Lead Sponsor:

ECOG-ACRIN Cancer Research Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Hodgkin Lymphoma

Non-Hodgkin Lymphoma

Eligibility:

All Genders

18+ years

Brief Summary

This study examines the impact of social and genetic factors on outcomes in adolescent and young adult (AYA) cancer survivors of Hodgkin or non-Hodgkin lymphoma. Compared to both older adult and child...

Detailed Description

PRIMARY OBJECTIVE: I. To establish the association of social-environmental risk factors on both disease-free survival (DFS) and overall survival (OS) for adolescent and young adult cancer survivors. ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Patient must be \>= 18 years of age at the time of registration
  • Patient must have been between the ages of 15-39 at the time of their first primary cancer diagnosis of Hodgkin lymphoma or non-Hodgkin lymphoma (NHL)
  • Patient must have completed therapy (with a complete response, per clinician determination) at the time of registration
  • Patients last date of prior systemic therapy for first primary diagnosis for Hodgkin lymphoma or non-Hodgkin lymphoma must have been within one year prior to registration
  • NOTE: Systemic therapy refers to all anti-cancer therapy, including but not limited to chemotherapy, intravenous (IV) or oral targeted medications, or radiation, and administered via a clinical trial or standard approach
  • Patient must have an Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-3
  • Patient must be English speaking in order to be able to complete the required QOL forms on this study
  • NOTE: Sites cannot translate the associated QOL forms
  • Patient must not be receiving active therapy for Hodgkin lymphoma or non-Hodgkin lymphoma
  • Patient must have internet access through computer, tablet, or smartphone
  • Patient must have email address
  • Patient must have the ability to understand and the willingness to sign a written informed consent document. Patients with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) or caregiver and/or family member available will also be considered eligible

Exclusion

    Key Trial Info

    Start Date :

    October 13 2023

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    February 1 2030

    Estimated Enrollment :

    2000 Patients enrolled

    Trial Details

    Trial ID

    NCT06002828

    Start Date

    October 13 2023

    End Date

    February 1 2030

    Last Update

    December 30 2025

    Active Locations (428)

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    Page 1 of 107 (428 locations)

    1

    Anchorage Associates in Radiation Medicine

    Anchorage, Alaska, United States, 98508

    2

    Anchorage Radiation Therapy Center

    Anchorage, Alaska, United States, 99504

    3

    Alaska Breast Care and Surgery LLC

    Anchorage, Alaska, United States, 99508

    4

    Alaska Oncology and Hematology LLC

    Anchorage, Alaska, United States, 99508