Status:

RECRUITING

CACIPLIQ20 in Wound Healing in Subjects With Epidermolysis Bullosa

Lead Sponsor:

Organ, Tissue, Regeneration, Repair and Replacement

Collaborating Sponsors:

Euraxi Pharma

ARANZ Medical

Conditions:

Epidermolysis Bullosa Dystrophica

Epidermolysis Bullosa, Junctional

Eligibility:

All Genders

3-18 years

Phase:

NA

Brief Summary

Epidermolysis bullosa (EB) is a group of inherited disorders characterized by fragility of the skin and mucous membranes within the basement membrane zone. It is characterized by moderate to excessive...

Detailed Description

The patients are outpatients at inclusion and may be already followed by the investigators, and they have not yet been treated with CACIPLIQ20 for at least one month. These patients will be randomly ...

Eligibility Criteria

Inclusion

  • Diagnosis of Dystrophic or Junctional EB.
  • 3 years ≤ age ≤ 18 years
  • At least one active wound at inclusion
  • Informed consent form signed by the patient's legal representative; if the patient is minor but capable of providing consent, additional signed consent from the patient.
  • Patient and caregiver must be willing to comply with all protocol requirements.

Exclusion

  • Use of any investigational drug within the last 30 days before enrolment.
  • Current or former malignancy.
  • Pregnancy or breastfeeding during the study.
  • Females of childbearing potential who are not abstinent and not practicing a medically acceptable method of contraception.
  • Use of CACIPLIQ20 within the last 30 days before enrolment.
  • Patients intolerant to one of the study device components or to heparinoids.

Key Trial Info

Start Date :

January 29 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2024

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT06007235

Start Date

January 29 2024

End Date

September 1 2024

Last Update

February 13 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hopital Necker - enfants malades

Paris, France, 75000

CACIPLIQ20 in Wound Healing in Subjects With Epidermolysis Bullosa | DecenTrialz