Status:
RECRUITING
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
Lead Sponsor:
Mayo Clinic
Conditions:
Cancer
Cancer Gene Mutation
Eligibility:
All Genders
18+ years
Brief Summary
This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients wit...
Eligibility Criteria
Inclusion
- GROUP A: Germline and Somatic Testing
- Has Mayo Clinic medical record number
- Confirmed cancer diagnosis which is either recurrent, relapsed, refractory, metastatic, or advanced
- Participant aware of cancer diagnosis
- Able to provide informed consent
- Ability to provide blood, saliva, bone marrow aspirate or hair follicle sample
- Ability to provide archived tissue, Note: if tissue unavailable participant may still enroll onto the study for the germline collection, or vice versa, if germline has already been completed may still enroll for somatic tissue testing.
- GROUP B: Germline testing only:
- Has Mayo Clinic medical record number
- Confirmed cancer diagnosis
- Participant aware of cancer diagnosis
- Able to provide informed consent
- Ability to provide blood, saliva, or hair follicle sample
Exclusion
- Note: Women who are pregnant or planning to become pregnant can take part in this study.
- GROUP A: Germline and Somatic testing
- Individuals who have situations that would limit compliance with the study requirements
- Institutionalized (i.e. Federal Medical Prison)
- Prior germline genetic testing with a 100+ multi-gene panel within the last 1 year of enrollment, AND/OR
- Prior somatic tissue (250+ gene) testing within the prior 3 months of enrollment
- GROUP B: Germline testing only
- Individuals who have situations that would limit compliance with the study requirements
- Institutionalized (i.e. Federal Medical Prison)
- Prior germline genetic testing with a 100+ multi-gene panel within the last 1 year of enrollment
Key Trial Info
Start Date :
October 12 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2033
Estimated Enrollment :
350 Patients enrolled
Trial Details
Trial ID
NCT06008392
Start Date
October 12 2023
End Date
September 1 2033
Last Update
October 10 2025
Active Locations (3)
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1
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
2
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224
3
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905