Status:
UNKNOWN
The Dose Range of Remimazolam Besylate in Different Age Groups
Lead Sponsor:
Tongji Hospital
Collaborating Sponsors:
Renmin Hospital of Wuhan University
Wuhan University
Conditions:
Remimazolam
Anesthesia
Eligibility:
All Genders
45+ years
Phase:
NA
Brief Summary
This is a multicenter, randomized, parallel, controlled clinical study of patients at different ages underwent elective non-cardiac surgery under general anesthesia. The aim of this study is to explor...
Detailed Description
Surgery is an effective method to treat surgical diseases, prolong survival time and improve the quality of life, but patients often face the risk of postoperative complications. In general surgery pa...
Eligibility Criteria
Inclusion
- age above 45 years old;
- American Society of Anesthesiologists grade Ⅰ-II;
- patients undergoing tracheal intubation or laryngeal mask airway surgery under general anesthesia (intravenous anesthesia);
- Informed consent: patients voluntarily participated in the trial and signed the informed consent form.
Exclusion
- patients with cardiac function grade 3 or above;
- difficult to observe the pupil size of head or neck surgery patients;
- patients with multimodal anesthesia such as nerve block or spinal anesthesia compounded;
- patients known to be allergic to remimazolam besylate or benzodiazepines;
- major vascular surgery and the type of surgery that directly affects hemodynamics;
- patients with coagulation dysfunction, endocrine diseases or other hemodynamic conditions;
- minor surgery (operation duration \<1 hour);
- surgery lasting more than 4 hours;
- emergency surgery;
- patients with a history of drug or alcohol dependence;
- Subjects deemed unsuitable for the study by the investigator.
Key Trial Info
Start Date :
July 17 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
1876 Patients enrolled
Trial Details
Trial ID
NCT06009991
Start Date
July 17 2023
End Date
December 31 2025
Last Update
September 6 2023
Active Locations (1)
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1
ongji Hospital, Tongji Medical College, Huazhong Science and Technology University
Wuhan, Hubei, China, 430030