Status:
UNKNOWN
The Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of Melasma
Lead Sponsor:
Indonesia University
Conditions:
Melasma
Eligibility:
FEMALE
18-60 years
Phase:
PHASE3
Brief Summary
The goal of this clinical trial is to compare 3% Topical Tranexamic Acid with 4% Topical Hydroquinone as Therapy of Melasma in Patients with Skin Type III-V. The main question\[s\] it aims to answer a...
Eligibility Criteria
Inclusion
- Female patients diagnosed with melasma.
- 18-60 years old.
- Fitzpatrick skin type III to V.
- Willing to be a research subject (SP) and sign a consent sheet. research (informed consent).
Exclusion
- Are pregnant and/or breastfeeding
- History of taking hormonal contraceptives in the last 6 months
- History of topical melasma therapy: corticosteroids, tretinoin, hydroquinone, and Another therapy that lightens the skin in the last 2 weeks.
- Use oral systemic therapy or injection in melasma, such as oral acid tranexamic, oral antioxidant, vitamin C injection, and glutathione injection in 4 last week.
- History of superficial peeling therapy in the last 4 weeks.
- History of deep peeling, laser or mechanical abrasion therapy in the last 6 months.
- Use drugs that are photosensitizers such as phenytoin, tetracycline, spironolactone, and carbamazepine.
- History of bleeding disorders or being on blood-thinning therapy
- Allergy to tranexamic acid
- Difficulty in complying with treatment.
- Are experiencing symptoms of COVID-19, such as fever, cough, sore throat, loss of sense of taste or smell, red eyes, diarrhea, rash on the skin
Key Trial Info
Start Date :
June 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06010810
Start Date
June 1 2023
End Date
September 30 2023
Last Update
September 21 2023
Active Locations (1)
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1
Cipto Mangungkusumo Hospital
Jakarta, DKI Jakarta, Indonesia, 10430