Status:

UNKNOWN

Safety and Efficacy Evaluation of the Robotic Enhanced Error Training of Upper Limb Function in Post-stroke and Post TBI Participants

Lead Sponsor:

Reuth Rehabilitation Hospital

Collaborating Sponsors:

Loewenstein Hospital

BioXtreme

Conditions:

Stroke

Brain Injuries

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Background: Cerebrovascular accident \[CVA or commonly known as stroke\] and traumatic brain injury (TBI) are common causes of morbidity, and motor impairments. Many stroke and TBI patients encounter ...

Detailed Description

Background: Stroke and traumatic brain injury (TBI) are leading causes for morbidity, hospitalization, and extended injury of motor system as well as movement learning. It has been proven that roughly...

Eligibility Criteria

Inclusion

  • Hemiparesis due to first stroke (ischemic or hemorrhagic) or TBI;
  • At least 14 days after the stroke or brain injury onset;
  • No more than 18 months after stroke or brain injury onset;
  • At least 4 weeks of remaining hospitalization in inpatient or outpatient rehabilitation ward;
  • Voluntary provided informed consent obtained prior to any screening procedures;
  • Cognitive status: Montreal Cognitive Assessment (MoCA test) score ≥ 22 or Mini Mental State Examination (MMSE) score \> 24;
  • Upper extremity function: Score between 35 and 52 points out of 66 on the Fugl- Meyer (FG) test with sub scores of 21-32/36 for the upper arm and 14-20/24 for the wrist and hand.

Exclusion

  • Complete paralysis of the affected side;
  • Uncontrolled epilepsy;
  • Upper-limb pain \> 6 on 10-point Visual Analogue Scale (VAS);
  • Concomitant or past medical conditions that might interfere with the study (i.e. hemi spatial neglect, orthopedic problems, etc.);
  • Current participation in other interventional clinical study;
  • Fingers spasticity score on the affected hand \> 3 on Modified Ashworth Scale (MAS);
  • Pregnant or nursing women.

Key Trial Info

Start Date :

September 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT06010823

Start Date

September 1 2023

End Date

December 1 2024

Last Update

September 22 2023

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Loewenstein Rehabilitation Center

Raanana, Israel

2

Reuth Rehabilitation Hospital

Tel Aviv, Israel, 6902732