Status:
RECRUITING
Effects of Different Oxygen Concentrations on Pulmonary Complications in Patients Undergoing Radical Resection of Esophageal Cancer
Lead Sponsor:
China Medical University, China
Conditions:
Atelectasis, Postoperative
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
Radical operation of esophageal cancer is complicated and traumatic, and ventilation with one lung in lateral position and ventilation with both lungs after supine position requires long-term tracheal...
Detailed Description
Therefore, we should explore the most appropriate lung protection ventilation strategy to reduce the occurrence of pulmonary complications. The recommended standard of international expert group on lu...
Eligibility Criteria
Inclusion
- American Association of Anesthesiologists (ASA) patients with I-II physical condition;
- Patients with preoperative partial pressure of blood gas and oxygen greater than 80mmHg who were scheduled for elective esophageal cancer surgery were operated in the right lateral position first and then in the supine position.
Exclusion
- there is a history of acute lung injury with acute respiratory distress syndrome within three months;
- Heart failure (classified by new york Heart Association) is greater than grade IV,
- there is a serious liver and kidney dysfunction (children with grade B or C liver failure, glomerular filtration rate \< 30 ml/min);
- Body mass index \> 30kg/m2；
- coagulation dysfunction;
- Operation time exceeds 10h
- The amount of bleeding is more than 800ml, and the total fluid volume is more than 3000ml.
Key Trial Info
Start Date :
September 6 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06013098
Start Date
September 6 2023
End Date
September 30 2026
Last Update
February 9 2024
Active Locations (1)
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1
the First Hospital of China Medical University
Shenyang, Liaoning, China, 110001