Status:
ENROLLING_BY_INVITATION
Twins MR Imaging Study
Lead Sponsor:
King's College London
Collaborating Sponsors:
Guy's and St Thomas' NHS Foundation Trust
Conditions:
Aging
Eligibility:
All Genders
18+ years
Brief Summary
This study aims to create a comprehensive Magnetic Resonance Imaging data resource in twins aged 18 years and older. The data will be used alone or in conjunction with existing data to explore organ-s...
Detailed Description
BACKGROUND Diverse interactions between environmental, genetic, and epigenetic factors shape individual paths of ageing and disease. In young adulthood, twins are highly similar in most organ structur...
Eligibility Criteria
Inclusion
- Identical or non-identical twins
- Gender: Male or Female
- Age: 18 years or above at the time of recruitment
- Must be able to understand the study information and provide informed consent
- Participation in the TwinsUK Biobank
Exclusion
- Pregnancy
- Unable to tolerate MRI Procedures, e.g., claustrophobia, severe anxiety
- Contraindication to MRI Scanning, e.g., presence of non-MR conditional implants
- Any additional condition declared voluntarily by the participant that the principal investigator (PI) deems likely to affect the study's outcome.
Key Trial Info
Start Date :
December 19 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2028
Estimated Enrollment :
2500 Patients enrolled
Trial Details
Trial ID
NCT06014567
Start Date
December 19 2023
End Date
March 1 2028
Last Update
January 25 2024
Active Locations (1)
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1
King's College London
London, United Kingdom, SE1 7EH