Status:

UNKNOWN

Fat Grafting for Vaginal Stenosis in Gynaelogical Cancer

Lead Sponsor:

Royal Marsden NHS Foundation Trust

Conditions:

Cervical Cancer

Eligibility:

FEMALE

Phase:

NA

Brief Summary

The GRASS study looks at performing a technique called "Fat Tissue Grafting" to assess whether it can reduce the side effects of vaginal stenosis effects and improve the sexual function of participant...

Detailed Description

Vaginal stenosis is a common sequelae of radiotherapy treatment for cervical cancer. This can cause significant sexual problems resulting in sexual avoidance, relationship problems, feelings of low se...

Eligibility Criteria

Inclusion

  • Patients with cervical cancer
  • At least 2 years since finishing pelvic radiotherapy for gynaecological cancer
  • Treated at RM
  • Persistent symptoms of vaginal stenosis despite prior use of vaginal dilators/ oestrogen replacement / lubricants/moisturisers
  • Desiring vaginal intercourse

Exclusion

  • Evidence of recurrent disease documented on Magnetic Resonance Imaging (MRI)
  • Patients unwilling / unable to provide written informed consent for the study

Key Trial Info

Start Date :

October 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2025

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT06015360

Start Date

October 1 2023

End Date

September 1 2025

Last Update

October 5 2023

Active Locations (1)

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1

The Royal Marsden NHS Foundation Trust

London, United Kingdom, SW36JJ