Status:

COMPLETED

Effect of Sourdough Bread Consumption on Postprandial Responses, Appetite Regulation and Energy Intake

Lead Sponsor:

KU Leuven

Conditions:

Appetite

Satiety

Eligibility:

All Genders

18-50 years

Phase:

NA

Brief Summary

During this project the effect of yeast bread and sourdough breads consumption on satiety, energy intake at subsequent meal and postprandial metabolic responses, will be investigated.

Detailed Description

The primary aim of this study will be to evaluate the impact of an alternative starter culture that produces high levels of lactic acid on appetite regulation (subjective satiety and energy intake at ...

Eligibility Criteria

Inclusion

  • Female and male participants
  • age range 18 - 50
  • BMI range 18.5 - 25.0 kg/m2 at screening visit
  • Regular eating pattern (3 meals per day on at least 5 days per week)
  • Stable body weight for the last 6 months

Exclusion

  • Currently smoking (has smoked in the last 28 days) or willingness to smoke during the study period
  • Pregnancy, lactation or wish to become pregnant during the study period
  • Family history of diabetes
  • Previous or current gastrointestinal or endocrine disorders
  • Previous or current substance/alcohol dependence or abuse (\> 2 units per day/14 units per week)
  • Coeliac disease or gluten sensitivity
  • Use of pre- or probiotics within one month preceding the study
  • Use of antibiotics within 3 months preceding the study
  • Excessive concern about eating habits or body weight as evidenced from scores \< 18 on the restraint and disinhibition subscales of the Three-Factor Eating Questionnaire (Stunkard \& Messick, 1985)

Key Trial Info

Start Date :

January 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 28 2024

Estimated Enrollment :

47 Patients enrolled

Trial Details

Trial ID

NCT06015867

Start Date

January 1 2024

End Date

April 28 2024

Last Update

May 14 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

KU Leuven/UZ Leuven

Leuven, Vlaams Brabant, Belgium, 3000

2

UZ Leuven

Leuven, Belgium, 3000