Status:
RECRUITING
Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals with High-Risk of Lung Cancer Undergoing LDCT Screening.
Lead Sponsor:
The Institute of Molecular and Translational Medicine, Czech Republic
Collaborating Sponsors:
Cancer Research Foundation CR
Conditions:
Lung Cancer
Eligibility:
All Genders
55-74 years
Phase:
NA
Brief Summary
The trial will evaluate if the newly identified biomarkers of lung cancer in exhaled breath condensate are as a diagnostic tool comparable to the low-dose computer tomography (LDCT) implemented in lun...
Detailed Description
The project aims to validate newly identified biomarkers of lung cancer in breath condensate for the diagnosis and triage of lung nodules (malignant versus benign), further set the mechanisms of the f...
Eligibility Criteria
Inclusion
- Consent to participate in a clinical trial.
- A clients within an age of 55-74 years.
- Current smoker or ex-smoker who has smoked at least 20 pack-years, provided that:
- priority will be given to clients who have smoked at least 30 pack-years.
- preference will be given to a former smoker who has not smoked for less than 15 years.
Exclusion
- Previous diagnosis of lung cancer.
- Progressing malignant tumor on symptomatic treatment.
- Advanced dementia
- Chronic obstructive pulmonary disease or other inflammatory disease in the phase of acute exacerbation.
Key Trial Info
Start Date :
June 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2030
Estimated Enrollment :
3200 Patients enrolled
Trial Details
Trial ID
NCT06016569
Start Date
June 1 2023
End Date
December 1 2030
Last Update
October 1 2024
Active Locations (3)
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1
Masaryk Memorial Cancer Institute
Brno, Czechia, 65653
2
University Hospital
Olomouc, Czechia, 77900
3
General University Hospital in Prague
Prague, Czechia, 12808