Status:
COMPLETED
The Bone-Myoregulation Reflex and Development of Sarcopenia in Osteoporosis
Lead Sponsor:
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Conditions:
Sarcopenia
Osteoporosis
Eligibility:
All Genders
20-85 years
Phase:
NA
Brief Summary
Bone and skeletal muscle are in a single unit that interacts with each other structurally and functionally. The aim of this study is to determine the contribution of bone myoregulation reflex as a neu...
Detailed Description
Bone and skeletal muscle are in a single unit that interacts with each other structurally and functionally. While myokines synthesized and released in skeletal muscle modulate the bone formation and d...
Eligibility Criteria
Inclusion
- For healthy young adults control Healthy volunteers aged 20-45 years
- For postmenopausal osteoporosis Hip DXA T-score (neck or total hip) \< -2.5
- For the Senile osteoporosis Over 65 years Male Hip DXA T-score (neck or total hip) \< -2.5 Female
Exclusion
- Osteopenic cases
- Possible sarcopenia (according to EWGSOP2 criteria)
- Vertigo
- Kidney stone
- Panic attack story
- Secondary osteoporosis
- Those with polyneuropathy, central nervous system disease clinic/history
- Myopathies (steroid, vitamin D deficiency, primary muscle diseases, etc.)
- Cases with lesions on the soleus skin
- History of fracture in lower extremity, joint prosthesis
- Lower extremity active/acute thrombophlebitis
Key Trial Info
Start Date :
August 29 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 29 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06017245
Start Date
August 29 2023
End Date
December 29 2023
Last Update
January 17 2024
Active Locations (1)
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1
Ilhan Karacan
Istanbul, Kocaeli, Turkey (Türkiye), 34303