Status:
UNKNOWN
Clinical Application of Super-resolution Ultrasound(SR-US) Imaging in Solid Tumors
Lead Sponsor:
Chinese PLA General Hospital
Conditions:
Neoplasms, Liver
Neoplasms Malignant
Eligibility:
All Genders
18-80 years
Brief Summary
It has well accepted that tumor angiogenesis present aberrant vascular architecture and functional abnormalities, which is associated with tumorigenesis, tumor propagation and progression. By locating...
Detailed Description
In this study, 7 indexes were obtained by ultrasonic acquisition. These 7 indicators are used to describe and evaluate the microvessels in the tumor, so as to achieve the early identification and diag...
Eligibility Criteria
Inclusion
- Age over 18 years old, gender unlimited;
- Patients with solid organ tumors with a maximum diameter \> 1cm;
- No contraindications with contrast ultrasound agents;
- It can improve the pathological results of the tumor or the diagnostic results supported by other relevant imaging tests.
- Patients can understand the purpose of the examination, voluntarily participate and sign the informed consent.
Exclusion
- The subject is known to be allergic to any component of the contrast agent Sonovue;
- Lesions were diffuse or borderless on contrast ultrasound;
- Patients who underwent previous anti-angiogenesis and chemotherapy, or other local treatment of the tumor;
- Poor image display or deep position in conventional ultrasound evaluation (\<10 cm from skin),
- The researchers determined that there were any other factors that were not suitable for inclusion or affected participants' participation in the study
- Patients with severe heart disease or lung disease;
- Patients who are pregnant, may be pregnant or breastfeeding;
- No enhanced MRI or enhanced CT results can be obtained;
- The investigator considers the subjects unfit to participate in this study.
Key Trial Info
Start Date :
June 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 28 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06018142
Start Date
June 1 2022
End Date
February 28 2025
Last Update
August 30 2023
Active Locations (1)
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1
Department of Interventional Ultrasound of Chinese PLAGH
Beijing, China