Status:
NOT_YET_RECRUITING
Bioactive Lipids & PBMC
Lead Sponsor:
Université Catholique de Louvain
Conditions:
Healthy
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The investigators aim at harvesting PBMC from healthy donors to study the effect of the lipids mediators of interest. After isolation from the blood, PBMC will be activated as largely reported in the ...
Detailed Description
Data from the scientific literature support the hypothesis that bioactive lipids play an important role in inflammatory disorders. The levels of these bioactive lipids are altered in several pathophys...
Eligibility Criteria
Inclusion
- Volunteers must be able to give informed consent to be included in the study.
- no chronic inflammatory disease
- no acute inflammation
Exclusion
- Men and women aged less than 18 years
- Pregnant women
- Prior diagnosis of a chronic inflammatory disease (for instance IBD, COPD, lupus, MS, etc. This is not an exhaustive list).
- Recent (\<21 days) episode of acute inflammation or immune-altering event (e.g. cold, flu, vaccine, …).
- Chronic or recent use of drugs interfering with the immune / inflammatory response. Examples include (and are not limited to) NSAIDs, corticosteroids, aspirin, mABs, etc.
- Unable to give informed consent
Key Trial Info
Start Date :
September 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2030
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06018259
Start Date
September 1 2023
End Date
May 1 2030
Last Update
August 30 2023
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