Status:
ACTIVE_NOT_RECRUITING
The Effect of Intermittent Fasting on Brain Health
Lead Sponsor:
University of Oklahoma
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Intermittent Fasting
Aging
Eligibility:
All Genders
55-80 years
Phase:
NA
Brief Summary
The central hypothesis of this study is that closer adherence to time restricted eating (TRE) will improve endothelial function, neurovascular (NVC) responses, resulting in improved cognitive performa...
Detailed Description
This hypothesis will be tested by assessing the effect of TRE (not more than 10hr eating window each day for 6 months) in healthy older adults (55-80 years of age).
Eligibility Criteria
Inclusion
- Age ≥55 and ≤80 years of age
- Adequate hearing and visual acuity to participate in the examinations
- Ability to read and write in English
- Competence to provide informed consent.
- Mini Montreal Cognitive Assessment ≥12
- Mini Nutritional Assessment ≥12
Exclusion
- Vision or hearing impairment that would impair the ability to complete study assessments
- Active CNS disease including multiple sclerosis, uncontrolled seizures, active brain cancer
- Cerebrovascular accident other than TIA within 60 days prior to Visit 0
- Major psychiatric disease, including major depression not currently controlled on medications, alcohol or drug abuse
- Diabetics prescribed sulfonylureas, meglitinides, and insulin
- Any other medical condition which, in the opinion of investigator, would render the patient inappropriate or too unstable to complete the study protocol
Key Trial Info
Start Date :
May 13 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2026
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT06019195
Start Date
May 13 2024
End Date
December 31 2026
Last Update
July 30 2025
Active Locations (1)
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1
Translational GeroScience Laboratory
Oklahoma City, Oklahoma, United States, 73117