Status:
UNKNOWN
Impacts of Different ART Regimens on Lipid Metabolism in People Living With HIV
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Conditions:
HIV Infection
Combined Antiretroviral Therapy
Eligibility:
All Genders
18+ years
Brief Summary
To compare the dynamic changes of lipid metabolism of people living HIV who treated with different antiretroviral therapy (ART) regimens such as Biktarvy EVG/c/TAF/FTC, DTG/FTC/TDF, TDF/3TC/EFV, etc. ...
Detailed Description
This was a prospective observational study aiming to evaluate dynamic changes of lipid metabolism in people living HIV who treated with different antiretroviral therapy (ART) regimens. At the same tim...
Eligibility Criteria
Inclusion
- People with HIV aged 18 years and older
- Treated with stable antiretroviral therapy
- Plasma HIV-1 RNA below 50 copies per milliliter for at least six months
- Without other comorbidities or concomitant medications
- Good compliance and can cooperated with the follow-up
- Willing to participate in the study and sign informed consent.
Exclusion
- Pregnant or breast-feeding
- Patients with poor treatment compliance
- Patients refused to attend the regular follow-up examination
- Patients with severe cardiovascular and cerebrovascular diseases or liver and kidney dysfunction
- Acute infection (malaria, tuberculosis, helminthiasis, pneumonia, meningitis), moderate or severe malnutrition and diarrhea in the last 3 months
- Take medications that may interfere with lipid metabolism throughout the study, such as statins/fibrates, antidiabetic
- Participated in other clinical trials within 3 months.
- Patients with severe mental illness
Key Trial Info
Start Date :
April 25 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2024
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT06019273
Start Date
April 25 2022
End Date
May 1 2024
Last Update
September 1 2023
Active Locations (1)
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1
Zhikai Wan
Hangzhou, Zhejiang, China, 310000