Status:

COMPLETED

Efficacy and Safety of Dexmedetomidine to Bupivacaine in Supraclavicular Brachial Plexus Block

Lead Sponsor:

Kafrelsheikh University

Conditions:

Dexmedetomidine

Bupivacaine

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The study aims to evaluate the analgesic efficacy and safety of addition of 1µg/kg dexmedetomidine to 20ml bupivacaine compared to 20ml and 30ml bupivacaine without additives in ultrasound-guided supr...

Detailed Description

Dexmedetomidine, a highly selective α2 adrenergic agonist, has been used as an adjuvant to local anesthetics. Various clinical trials performed have shown dexmedetomidine to be safe when used as an ad...

Eligibility Criteria

Inclusion

  • American Society of Anesthesiologist (ASA) grade I or II patients
  • both sexes
  • scheduled for elective upper limb surgery below mid-humerus level under Ultrasound -guided Supraclavicular brachial plexus block .

Exclusion

  • with pre-existing peripheral neuropathy of upper limb.
  • Bleeding disorders.
  • Infection at injection site.
  • Untreated pneumothorax.
  • Patients on adrenoreceptor agonist or antagonist therapy.
  • History of severe cardiac,.respiratory, hepatic, or renal disease.
  • pregnancy and known hypersensitivity to the study drugs.

Key Trial Info

Start Date :

October 9 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 11 2024

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT06020781

Start Date

October 9 2023

End Date

March 11 2024

Last Update

April 2 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Kafrelsheikh University

Kafr ash Shaykh, Kafrelsheikh, Egypt, 33516