Status:
RECRUITING
Standard Dose Continuous Renal Replacement Therapy (CRRT) Versus Low-Dose CRRT ( KETZEREI )
Lead Sponsor:
Universität Münster
Conditions:
Critical Illness
Acute Kidney Injury
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Acute kidney injury (AKI) is a well-recognized complication in critically ill patients, which often leads to the necessity of mechanical kidney support (CRRT). In current therapeutic regimes, CRRT is...
Eligibility Criteria
Inclusion
- Adult patients (age ≥18 years)
- Critically ill patients with AKI + in need of CRRT
- Written informed consent
Exclusion
- Chronic dialysis dependency
- Chronic kidney disease with estimated glomerular filtration rate (eGFR) \<30 ml/min/1.73m²
- severe liver cirrhosis (Child-pugh C)
- severe acidosis (pH \< 7,20 at study enrolment)
- severe hyperkalaemia (\> 6mmol/l)
- Pregnancy or breastfeeding
- persons held in an institution by legal or official order
- Dependency on the investigator or center
Key Trial Info
Start Date :
October 2 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
165 Patients enrolled
Trial Details
Trial ID
NCT06021288
Start Date
October 2 2023
End Date
June 30 2025
Last Update
November 27 2024
Active Locations (2)
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1
University Hospital Münster
Münster, Germany, 48149
2
Universitätsklinikum Tübingen; Universitätsklinik für Anästhesiologie und Intensivmedizin
Tübingen, Germany, 72076