Status:

UNKNOWN

Koebner's Phenomenon in Psoriasis and Lichen Planus

Lead Sponsor:

Marie-Charlotte Brüggen

Conditions:

Kobner Phenomenon

Psoriasis

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Psoriasis and lichen planus often occur at mechanically irritated skin sites (e.g. tight clothing). The investigators would like to investigate this phenomenon in more detail in this study. For this p...

Eligibility Criteria

Inclusion

  • Dermatologist diagnosed psoriasis (group psoriasis), lichen planus (group lichen planus) or no skin disease (group healthy controls)
  • Subject is capable of giving informed consent
  • Signed informed consent

Exclusion

  • Use of systemic immunosuppressive/immunmodulating agents in the last three months
  • Use of topical anti-inflammatory treatment in the last 7 days in the area of sampling.
  • Phototherapy in the last 4 weeks
  • Active or recurrent serious bacterial, fungal or viral infection at the time of enrollment by patient history, including patients with Human Immunodeficiency Virus (HIV) infection, Hepatitis B and Hepatitis C infection, active or untreated latent tuberculosis.
  • Female patients of childbearing potential who are pregnant or breast feeding or planning a pregnancy during the duration of the trial and/or not practicing acceptable birth control for the duration of the trial
  • Known or suspected non-compliance, drug or alcohol abuse,
  • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,
  • Previous enrolment into the current study,
  • Enrolment of the investigator, his/her family members, employees and other dependent persons.

Key Trial Info

Start Date :

September 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2025

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT06021405

Start Date

September 15 2023

End Date

June 30 2025

Last Update

September 1 2023

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