Status:
ACTIVE_NOT_RECRUITING
The MARY-JANE Cannabis and Heart Rhythm Trial
Lead Sponsor:
University of California, San Francisco
Conditions:
Premature Atrial Contractions
Premature Ventricular Contractions
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
Despite recreational cannabis now being legal in 23 states, where more than 100 million Americans reside, studies on the actual health effects are limited. This study is a randomized trial, where each...
Detailed Description
This study is designed as a case-crossover randomized trial, where each participant will be instructed to consume or avoid inhaled cannabis on randomly assigned days during a 14-day monitoring period....
Eligibility Criteria
Inclusion
- Are age 21 or older
- Have a smartphone
- Are able to use the Eureka mobile application and Mosio text messaging software
- Have inhaled cannabis in the past month and on at least four different days in the same week in the past year
- Are willing to consume and abstain from inhaled cannabis for no more than two consecutive days as instructed over the 14-day trial period
- Are able to participate in a location where cannabis use would not break any established laws under any jurisdiction
- Are able to self supply cannabis throughout the study duration
Exclusion
- Currently pregnant or trying to get pregnant
- Have a medical reason to avoid cannabis
- Are unwilling to avoid all forms of cannabis consumption on days instructed to abstain from cannabis
- Are currently taking anti-arrhythmic medications
- Have a history of atrial fibrillation or heart failure
- Have congenital heart disease
- Have an implantable cardioverter-defibrillator or pacemaker
- Have had a previous cardiac ablation procedure
- Are currently taking insulin
- Are unable to read or sign to provide informed consent
Key Trial Info
Start Date :
January 18 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06021613
Start Date
January 18 2024
End Date
November 1 2026
Last Update
June 29 2025
Active Locations (2)
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1
UCSF Medical Center at Parnassus
San Francisco, California, United States, 94143
2
UCSF Medical Center at Mission Bay
San Francisco, California, United States, 94158