Status:
COMPLETED
Effect of a Two-month Carbohydrate-restricted Diet on Energy Metabolism in a Seniors' Residence
Lead Sponsor:
Université de Sherbrooke
Conditions:
Healthy Aging
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
The present study will assess the effects on glucose, ketones and other blood biomarkers fuels, cognition, quality of life, physical activity and well-being of a reduced carbohydrate menu (R-CHO) for ...
Detailed Description
Finding an effective therapeutic strategy for Alzheimer's disease (AD) is a societal priority, but it also remains a major challenge. With one exception in 2021, no new pharmaceutical treatment for AD...
Eligibility Criteria
Inclusion
- Senior men or women residing in VÜ resident home;
- Understand, read and write French;
- Possess sufficient visual and auditory acuity to pass the cognitive tests;
- Available during the intervention period
Exclusion
- Body mass index \< 20;
- T1 diabetic;
- Insulin-dependent T2 diabetic;
- Mini Mental State Exam (MMSE) \< 20;
- Weight loss \>10% in the last 6 months, involuntary or voluntary;
- Known and uncontrolled hypoglycaemia;
- Moderate to severe digestive illnesses that may be aggravated by dietary changes;
- Severe dysphagia;
- Supplementation with medium chain triglycerides oil, ketone salts, ketone ester, adherence to the ketogenic diet, reduced carbohydrate diet, intermittent fasting, or other diet or supplements that may significantly increase ketones in the past month;
- Participation in other intervention research projects on nutrition or aimed at metabolic change simultaneously.
- Medical condition that could prevent the participant from completing the study according to the doctor's opinion
Key Trial Info
Start Date :
September 10 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 15 2024
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT06022094
Start Date
September 10 2023
End Date
May 15 2024
Last Update
June 3 2024
Active Locations (1)
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1
Research Center on Aging
Sherbrooke, Quebec, Canada, J1H 4C4