Status:
RECRUITING
Quantitative Sensory Testing and Occipital Nerve Stimulator
Lead Sponsor:
Barts & The London NHS Trust
Conditions:
Migraines
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary aim of this study is to assess the reversibility of a range of psychophysical markers of pain processing in patients with chronic migraine or cluster headache before and after ONS insertio...
Detailed Description
Headache is one of the most common neurological problems accounting for 4% of primary care consultations and up to 30% of neurology appointments. Even though considerable advances in the understanding...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Subject satisfies standard criteria in the study centre for ONS implantation and the NICE 452 criteria for intractable chronic migraine or cluster headache.
- Patients who have given their written informed consent.
- Patient is able and willing to comply with study procedures and follow up schedule.
- Participants will need a good understanding of the English Language and hence. This is a requirement not just for this research but also for the success of the interventions and the full understanding of QST.
- Patients undergoing surgery (non-painful complaint) 'dilatation and curettage' (D\&C).
- Exclusion criteria
- Any inclusion criteria not met
- Female patients of childbearing age who is or plans on becoming pregnant during the course of the study
- Patients with diabetes
- Patients known to have a condition that in the investigator's judgment precludes participation in the study.
- Patients who have received an investigational drug or have used an investigational device in the 30 days preceding to study entry
Exclusion
Key Trial Info
Start Date :
September 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2025
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06022848
Start Date
September 1 2019
End Date
November 1 2025
Last Update
May 13 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Barts health NHS Trust
London, United Kingdom, EC1A7BE