Status:

UNKNOWN

Submucosal Saline Injection Followed by Endoscopic Ultrasound

Lead Sponsor:

Sun Yat-sen University

Collaborating Sponsors:

Zhejiang Cancer Hospital

Sichuan Cancer Hospital and Research Institute

Conditions:

Esophageal Cancer

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Endoscopic ultrasound (EUS) is unsatisfactory in distinguishing between T1a and T1b stage esophageal squamous cell carcinoma (ESCC). Consequently, the National Comprehensive Cancer Network guidelines ...

Eligibility Criteria

Inclusion

  • Age 18-75 years old, no gender limited;
  • Patients with esophageal squamous cell carcinoma who be confirmed by ordinary endoscopy and pathologic biopsy;
  • Patients who agree to accept endoscopic resection or surgical excision of the lesion in esophagus;
  • patients with normal cardio-pulmonary function and normal coagulative function,are predicted to be tolerated anesthesia and surgery;
  • patients who understand test purpose, volunteer to join these study and sign the consent inform.

Exclusion

  • Patients with stages of T2, T3, or T4 displayed by EUS;
  • Patients who can't tolerate endoscopy and surgical treatment for various reasons;
  • Patients who have distant metastasis, or multiple source of malignant tumors;
  • Patients with blood coagulative disorder;
  • Patients don't accept the endoscopic examination or surgical treatment;
  • Patients with poor compliancy.

Key Trial Info

Start Date :

January 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 30 2024

Estimated Enrollment :

432 Patients enrolled

Trial Details

Trial ID

NCT06022978

Start Date

January 1 2021

End Date

December 30 2024

Last Update

September 5 2023

Active Locations (1)

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Cancer center, Sun Yat-sen University

Guangzhou, Guangdong, China, 510080