Status:

RECRUITING

An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan

Lead Sponsor:

AbbVie

Conditions:

Crohn's Disease

Eligibility:

All Genders

15+ years

Brief Summary

Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. This study will assess how safe and effective upadacitinib is in treating moderately to severely activ...

Eligibility Criteria

Inclusion

  • Diagnosed with moderately to severely active Crohn's disease (CD).
  • Has been prescribed upadacitinib for CD as per most current local approved label after its approval for CD in Japan.
  • Within 14 days from the commencement of upadacitinib induction treatment for CD at the participating institution.

Exclusion

  • Currently participating in another interventional clinical research.
  • Participants for whom upadacitinib is contraindicated.
  • Has been treated with upadacitinib for CD before and continue treatment with upadacitinib for CD at the participation to this study.

Key Trial Info

Start Date :

July 28 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2026

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT06023030

Start Date

July 28 2023

End Date

November 1 2026

Last Update

April 17 2025

Active Locations (101)

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Page 1 of 26 (101 locations)

1

Anjou Kousei Hospital /ID# 261872

Anjo-shi, Aichi-ken, Japan, 446-8602

2

Handa City Hospital /ID# 270446

Handa, Aichi-ken, Japan, 475-8599

3

Aichi Medical University Hospital /ID# 261871

Nagakute, Aichi-ken, Japan, 480-1195

4

Masuko Memorial Hospital /ID# 267420

Nagoya, Aichi-ken, Japan, 453-0016

An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan | DecenTrialz