Status:
COMPLETED
Impact of Gingival Crevicular Fluid microRNAs on Orthodontic Tooth Movement
Lead Sponsor:
University of Catania
Conditions:
Orthodontic Tooth Movement
Eligibility:
All Genders
11-18 years
Phase:
NA
Brief Summary
A split-mouth study is conducted in order to evaluate the impact of orthodontic movement on the expression of gingival crevicular fluid miRNAs related to inflammation and osteoclastogenesis during can...
Detailed Description
A split-mouth study is conducted in order to evaluate the impact of orthodontic movement on the expression of gingival crevicular fluid miRNAs related to inflammation and osteoclastogenesis during can...
Eligibility Criteria
Inclusion
- patients with excellent oral hygiene throughout the study period,
- patients requiring asymmetrical maxillary first premolar extraction so monolateral canine retraction will be performed as a part of the treatment,
- patients available to come back at the clinic at the times of sample collection.
Exclusion
- poor oral hygiene and/or bleeding on probing,
- use medications, steroids or other anti-inflammatory medications,
- systemic health problems or smoking.
Key Trial Info
Start Date :
May 15 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2023
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT06023433
Start Date
May 15 2020
End Date
September 30 2023
Last Update
December 4 2023
Active Locations (1)
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1
AOU Policlinico G. Rodolico
Catania, Italy, 95124