Status:
RECRUITING
Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing
Lead Sponsor:
Professor Ernest Hung-Yu Ng
Conditions:
Infertility
Genetic Disease
Eligibility:
All Genders
Up to 43 years
Phase:
NA
Brief Summary
Infertile women attending for PGT at the Centre of Assisted Reproduction and Embryology, Queen Mary Hospital and Kwong Wah Hospital will be recruited during ovarian stimulation for IVF. Subsequently, ...
Detailed Description
The study aims to investigate the treatment of couples undergoing in vitro fertilization (IVF). Eligible couples will be recruited for the study after providing informed written consent following coun...
Eligibility Criteria
Inclusion
- Women aged \<43 years at the time of ovarian stimulation for IVF
- Women undergoing PGT for monogenic diseases, structural rearrangement of chromosomes or aneuploidy
- Sperm concentration of the raw semen with at least 0.15 million motile sperm per ml or 100 motile sperm per 50 low power field (200x) of observation
Exclusion
- Use of frozen semen for insemination
- Use of donor oocytes and spermatozoa
- Submucosal fibroid or hydrosalpinx shown on pelvic scanning and not surgically treated;
- Women who had been recruited into this study before and
- Women joining other randomized trials
Key Trial Info
Start Date :
November 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2028
Estimated Enrollment :
318 Patients enrolled
Trial Details
Trial ID
NCT06023472
Start Date
November 1 2024
End Date
November 30 2028
Last Update
December 6 2024
Active Locations (1)
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1
Department of Obstetrics and Gynaecology
Hong Kong, Hong Kong, China