Status:
COMPLETED
The Importance of Prostaglandin and Nitric Oxide Synthesis in Apical Periodontitis
Lead Sponsor:
Istanbul Medipol University Hospital
Conditions:
Periapical Periodontitis
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
A total of 185 subjects were divided into three categories: AP group (n=85), CP group (n=50) and healthy control group (n=50). The AP group was divided into 3 subgroups according to abscess scoring (A...
Detailed Description
* Study Design This observational, analytical, cross-sectional study was conducted at a single center. In order to reach the planned sample size, approximately 1200 patients who applied to the Departm...
Eligibility Criteria
Inclusion
- Apical periodontitis (AP) and/or chronic periodontitis (CP)
- Patients who had taken antibiotics and/or anti-inflammatory drugs within the last 6 months - - Without periodontal pathology as well as any acute/chronic disease (muscle/joint/bone diseases, inflammatory bowel disease, local or generalized infection, severe organ disease, cardiovascular disease and diabetes mellitus) were included in the study
Exclusion
- with pregnancy or lactation were also excluded.
- with a history of using steroid or nonsteroidal anti-inflammatory drugs and high-dose biotin vitamin in the last 48 hours were excluded from the study.
Key Trial Info
Start Date :
January 7 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 2 2023
Estimated Enrollment :
185 Patients enrolled
Trial Details
Trial ID
NCT06023901
Start Date
January 7 2021
End Date
August 2 2023
Last Update
October 3 2024
Active Locations (1)
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1
Istanbul Medipol University, Faculty of Dentistry
Istanbul, ESENLER, Turkey (Türkiye), 34083