Status:

NOT_YET_RECRUITING

Role of MDSCs and Cancer Stem Cells and Their Cross Talks in NSCLC

Lead Sponsor:

University Hospital, Bordeaux

Conditions:

Lung Neoplasms

Myeloid-Derived Suppressor Cells

Eligibility:

All Genders

18+ years

Brief Summary

Immunotherapy have revolutionized the field of oncology, but response rates are low and all patients relapse, due to cellular and soluble immunosuppressive mechanisms. MDSC are one of the most importa...

Detailed Description

In recent years, immune-based therapies have revolutionized the field of oncology by significantly improving survival of cancer patients. Despite sustained responses, only 20% to 40% of cancer patient...

Eligibility Criteria

Inclusion

  • consecutive patients
  • lung carcinoma surgically treated by surgery only

Exclusion

  • patient receiving chemotherapy, radiotherapy or immunotherapy in the neoadjuvant setting (all objectives)
  • patient with concomitant or previous cancer (in the 2 years)

Key Trial Info

Start Date :

December 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06024226

Start Date

December 1 2025

End Date

December 1 2027

Last Update

July 30 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

CHU de Bordeaux - Hôpital Saint-André, Service d'Oncologie Médicale

Bordeaux, France, 33000

Role of MDSCs and Cancer Stem Cells and Their Cross Talks in NSCLC | DecenTrialz