Status:

UNKNOWN

Efficacy, Safety, and Treatment Patterns of Transcatheter Arterial Chemoembolization (TACE) Combined With Atezolizumab and Bevacizumab in Unresectable Hepatocellular Carcinoma: a Multicenter, Retrospective, Observational Real-world Study

Lead Sponsor:

Zhongda Hospital

Conditions:

HCC

Eligibility:

All Genders

18+ years

Brief Summary

This study will evaluate the efficacy and safety of TACE combined with atezolizumab + bevacizumab in the treatment of unresectable hepatocellular carcinoma, and the treatment patterns of the combinati...

Detailed Description

This study is a multi-center, retrospective and observational real-world study to explore the efficacy, safety and treatment pattern of TACE combined with Atezolizumab + Bevacizumab in unresectable he...

Eligibility Criteria

Inclusion

  • All patients were diagnosed with unresectable hepatocellular carcinoma according to the guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2019 Edition);
  • Patients ≥ 18 years old, male or female;
  • Child-Pugh Class A and B liver function;
  • ECOG-PS score of 0 \~ 2 points;
  • Received TACE in combination with atezolizumab + bevacizumab for at least one interval of no more than eight weeks.

Exclusion

  • Other primary malignancies;
  • Incomplete data, such as no baseline image that can be assessed according to RECIST 1.1 or mRECIST, and survival outcome.

Key Trial Info

Start Date :

September 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2024

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06024252

Start Date

September 1 2023

End Date

June 1 2024

Last Update

September 6 2023

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