Status:

WITHDRAWN

Study of ADI CardioPulmonary Management (CPM) System

Lead Sponsor:

Analog Device, Inc.

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study is meant primarily collect CardioPulmonary Management (CPM) data from daily usage and compare it to the clinical course of a patient. For this study, the only aspect of the CPM solution tha...

Detailed Description

Patients that participate in this study will be using a wearable device for 6 months. At their initial visit (visit 1), patients will undergo a brief physical exam, have their medical history and medi...

Eligibility Criteria

Inclusion

  • Heart failure (HF) patients regardless of ejection fraction, HFpEF (heart failure preserved ejection fraction) or HFrEF (heart failure reserved ejection fraction) with one or more of the following:
  • New York Heart Association (NYHA) Class III HF
  • NYHA Class IV HF OR
  • NYHA Class II HF with one/. or more of the following:
  • Chronic Kidney Disease (eGFR\<60 within the past 6 months)
  • HF hospitalization (defined as HF listed as the major reason for hospitalization) within 9 months prior to screening visit and NT-proBNP \> 200 pg/ml\* (N-terminal pro b-type natriuretic peptide) for patients not in atrial fibrillation (AF) or \> 600 pg/ml\* for patients in AF on screening ECG+
  • NT-proBNP \> 300 pg/ml\* for patients not in AF or \> 900 pg/ml\* for patients in AF on the screening visit ECG+
  • Chronic obstructive pulmonary disease (COPD)

Exclusion

  • Under 18 years of age
  • Patients with severe COPD (GOLD stage III or IV)
  • Limited mobility preventing application of device or no caregiver to assist
  • Cognitive impairments that would limit the application and proper use of the device
  • Skin allergies or skin sensitivities to silicone-based adhesives
  • Pregnancy (method of assessment at the discretion of the PI)
  • Not willing to shave chest hair if needed to apply device
  • Patients on chronic IV (intravenous) ionotropic therapy - (Milrinone, Dobutamine, and Dopamine)
  • Patients with any condition that might limit the survival to less than 1 year as assessed by the investigator
  • No cellular coverage (Patient's Home)\*\*
  • Skin breakdown on the left chest or breast area

Key Trial Info

Start Date :

March 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2024

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT06024369

Start Date

March 1 2024

End Date

March 1 2024

Last Update

May 16 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Tufts Medical Center

Boston, Massachusetts, United States, 02111