Status:
UNKNOWN
Evaluation of Diaphragmatic Function and Quadriceps Muscle Thickness in Patients Receiving High Protein Nutrition
Lead Sponsor:
Zagazig University
Conditions:
ICU Acquired Weakness
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Different Protein Doses' Effect on Diaphragmatic Function and Quadriceps Thickness
Detailed Description
Nutrition therapy is no longer a support method for critically ill patients but is considered an important treatment measure. Increasing the protein and energy available to patients in the intensive c...
Eligibility Criteria
Inclusion
- • Acceptance of the first-degree relatives.
- Critically ill patients: patients with a life-threatening condition that requires pharmacological and/or mechanical support of vital organ functions without which death would be imminent.
- Patients anticipated to be mechanically ventilated for ≥ 48 hours
- Patients who expected ICU stay ≥ 4 weeks
- Patients aged between 18 - 60 years of both sexes.
- Patient nutrition risk screening (NRS 2002) score ≥ 3
- Patient BMI less than 35
- No contraindication to early enteral nutrition.
Exclusion
- • Patient with Trauma to both lower extremities, diaphragm disease (trauma, immobilization….), myopathy, and moderate to severe hepatic insufficiency.
- Patient receiving steroids.
- Patient on renal replacement therapy.
- Prior MV before admission.
- Pregnant.
- Patient with neuromuscular disease, spinal cord injury, thoracic deformity, and respiratory restriction.
- Patients require muscle paralysis on MV.
- Patients require high dose inotrope or vasopressor.
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2024
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT06025760
Start Date
October 1 2023
End Date
November 1 2024
Last Update
September 14 2023
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.