Status:

ACTIVE_NOT_RECRUITING

Standardizing the Management of Patients with Coronary Microvascular Dysfunction

Lead Sponsor:

Consorzio Futuro in Ricerca

Collaborating Sponsors:

Università degli Studi di Ferrara

Abbott Medical Devices

Conditions:

Coronary Artery Disease

Microvascular Angina

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The SAMCRO is an all comers, prospective, randomized, multicenter, open-label study with blinded adjudicated evaluation of outcomes (PROBE). The diagnosis of angina in non obstructive coronary artery ...

Detailed Description

The aim of the SAMCRO trial is to determine whether a multidomain lifestyle intervention improves angina status and quality of life in ANOCA patients as compared to current standard of care. Patients...

Eligibility Criteria

Inclusion

  • Patient admitted to hospital for chronic coronary syndrome (CCS) with indication for coronary artery angiography
  • absence of obstructive coronary artery disease at invasive coronary artery angiography
  • Coronary microvascular dysfunction as identified by invasive coronary physiology

Exclusion

  • Planned coronary revascularization
  • Co-morbidity reducing life expectancy to less than 1 year
  • Any factor precluding 1-year follow-up
  • Prior Coronary Artery Bypass Graft (CABG) surgery
  • Presence of a chronic total occlusion (CTO)

Key Trial Info

Start Date :

October 10 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 4 2029

Estimated Enrollment :

123 Patients enrolled

Trial Details

Trial ID

NCT06025994

Start Date

October 10 2023

End Date

February 4 2029

Last Update

February 6 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

AOU Ferrara

Ferrara, Ferrara, Italy, 44124

2

AOU di Parma

Parma, Parma, Italy