Status:
RECRUITING
Blood Flow Regulation and Neuromuscular Function Post-Stroke
Lead Sponsor:
Medical College of Wisconsin
Conditions:
Stroke
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The muscles of stroke survivors can fatigue faster compared to muscles in people who have not had a stroke, which can limit how long a person with stroke can perform tasks such as walking. This study ...
Detailed Description
This study will examine peripheral blood flow regulation in the exercising muscle of stroke survivors and determine relationships between hyperemic blood flow and the functional sympatholysis magnitud...
Eligibility Criteria
Inclusion
- Be between 18-85 years of age
- Able to give informed consent
- ≥6 months post diagnosis of unilateral cortical or sub-cortical stroke
- English speaking
Exclusion
- History of blood clots in the extremities or any condition in which compression of the thigh or transient ischemia is contraindicated (e.g. wounds in the leg)
- Chronic pain syndrome
- Low back or hip pain that interferes with lower extremity motor testing
- History of head trauma
- Comorbid neurological disorder
- Peripheral vascular disease
- Myocardial infarction in the previous year
- Inability to follow 2 step commands
- Condition where fatiguing contractions or resisted leg contractions are contraindicated
- Resting SBP ≥160 mmHg or DBP ≥ 110 mmHg
- Pregnancy or breastfeeding.
Key Trial Info
Start Date :
January 11 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2028
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06027294
Start Date
January 11 2024
End Date
June 30 2028
Last Update
September 25 2025
Active Locations (2)
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1
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
2
Marquette University
Milwaukee, Wisconsin, United States, 53233