Status:
UNKNOWN
Iron Fortified Food to Improve Japanese Encephalitis and Typhoid Fever Vaccine Immunogenicity
Lead Sponsor:
University of Oxford
Collaborating Sponsors:
Mahidol University
Ministry of Health, Thailand
Conditions:
Iron Deficiency Anemia
Eligibility:
FEMALE
18-49 years
Phase:
NA
Brief Summary
Iron deficiency (ID) anaemia (IDA) is a global public health problem, with the highest prevalence in Africa and in South-East Asia. While immunization programs have achieved high global coverage, vacc...
Eligibility Criteria
Inclusion
- Participant is willing and able to give informed consent for participation in the trial.
- Female aged 18-49 years.
- Diagnosed with anaemia (i.e. hemoglobin (Hb) concentration \<12 g/dl), but no severe anaemia (Hb \<8 g/dl), and iron deficiency (ZnPP \>40 µmol/mol)
- Anticipated residence in the area for the study duration
Exclusion
- Pregnant (confirmed by rapid test during screening and at time of vaccination), lactating or planning pregnancy during the trial.
- Blood transfusion or intravenous iron treatment within 4 months of study start
- Major chronic infectious disease (e.g., tuberculosis, HIV+, hepatitis)
- Major chronic non-infectious disease (e.g., Type 1 or 2 diabetes, cancer)
- Treatment with supplemental iron two weeks prior to enrolment
- JE or typhoid vaccine within the past two years
Key Trial Info
Start Date :
September 6 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06027801
Start Date
September 6 2023
End Date
December 30 2024
Last Update
November 29 2023
Active Locations (1)
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1
Mahidol University
Roi Et, Thailand