Status:

UNKNOWN

Concurrent Training on Patients With Type-II DM Associated PAD.

Lead Sponsor:

Ziauddin University

Conditions:

Type 2 Diabetes With Peripheral Angiopathy

Eligibility:

All Genders

40-50 years

Phase:

NA

Brief Summary

This clinical trial aims to analyze the effects of concurrent vs aerobic training on glycemic control, ABI, functional capacity and disease-specific QOL among patients with Type-II DM-associated PAD a...

Detailed Description

DATA COLLECTION PROCEDURE; Eighty patients will be referred from the OPD of Dr. Ziauddin Hospital Karachi, Pakistan. Signed informed consent will be obtained before participation. In the screening se...

Eligibility Criteria

Inclusion

  • Age: 40 - 50 years
  • Type-II DM
  • Duration of DM: \> 10 years
  • Baseline HbA1C (\> 6.6%)
  • Intermittent claudication corresponding to Fontaine Stage IIa
  • PAD by an ABI scale; \< 0.9 at rest
  • Had \< 160 mmHg SBP and \< 105 mmHg DBP
  • Sedentary lifestyle by IPAQ-SF

Exclusion

  • Smokers
  • Insulin dependent individuals
  • Patients with Complicated cardiovascular disease that might limit their ability to - participate in the intervention period physically (e.g. unstable cardiopulmonary symptoms, ischemic heart failure, or chronic kidney disease) and cancer
  • Any major surgery or revascularization procedure within the previous 1 year
  • In case of a history of severe arthritis that may limit exercise performance
  • Diabetic foot (ulceration or gangrene)
  • Patients with stroke
  • BMI = \>30 classified by WHO-Asian as obesity class II
  • Unable to follow the intervention protocol or visit three times per week for exercise
  • Participation in any clinical trial during the past six months
  • Revocation to consent

Key Trial Info

Start Date :

July 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2023

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06028399

Start Date

July 15 2023

End Date

November 1 2023

Last Update

September 8 2023

Active Locations (1)

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1

Uroosa Amin

Karachi, Sindh, Pakistan, 74700