Status:

RECRUITING

International Active Surveillance Study: Native Estrogen Estetrol (E4) Safety Study

Lead Sponsor:

Center for Epidemiology and Health Research, Germany

Collaborating Sponsors:

Estetra

Gedeon Richter Plc.

Conditions:

Contraception

Birth Control

Eligibility:

FEMALE

Brief Summary

Multinational, comparative, prospective, active surveillance study that follows two cohorts. The primary objective of the study is to characterize and compare the risks of E4/Drospirenone (DRSP) with...

Detailed Description

Rationale and background: The combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP) (E4/DRSP) is a novel oral contraceptive containing a fixed dose of E4 (14.2 mg) and DR...

Eligibility Criteria

Inclusion

  • New users of E4/DRSP New users of EE/LNG Germany: only recruitment of study participants who are prescribed the COC within on-label use

Exclusion

  • \-

Key Trial Info

Start Date :

June 28 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 31 2028

Estimated Enrollment :

101000 Patients enrolled

Trial Details

Trial ID

NCT06028555

Start Date

June 28 2023

End Date

October 31 2028

Last Update

August 17 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Berlin Center for Epidemiology and Health Research

Berlin, State of Berlin, Germany, 10115