Status:
RECRUITING
Investigation of in Vivo Endogenous and/or Exogenous Production of Phenolic Metabolites Using (un)Targeted Metabolomics
Lead Sponsor:
University of Parma
Conditions:
Individual Variability in (Poly)Phenol Metabolism
Eligibility:
All Genders
20-40 years
Phase:
NA
Brief Summary
Plant (poly)phenols is what we call a large number of substances that are produced by plants as secondary plant metabolites, which means substances that are not used for their growth and development b...
Detailed Description
The study will consist of a randomized cross-over trial and each arm will last 5 days. A total of thirty (30) healthy volunteers will be recruited for the study in Parma (PR), using announcements plac...
Eligibility Criteria
Inclusion
- Apparently healthy adults,
- Age 20-40 years old,
- Body mass index (BMI) between 18-28,
- Regular coffee consumers (at least 1 cup a day).
Exclusion
- Clinical diagnosis of metabolic diseases,
- Clinical diagnosis of cardiovascular diseases,
- Clinical diagnosis of renal diseases,
- Clinical diagnosis of digestive diseases,
- Immunodeficiency
- Autoimmune diseases (other than well-compensated hypothyroidism),
- Mental disorders
- Regular use of medication (except birth-control pills and hormone replacement therapies),
- Use of antibiotics in the last month prior to enrollment,
- Food allergies or intolerances,
- Pregnancy
- Lactation
Key Trial Info
Start Date :
October 25 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06028659
Start Date
October 25 2023
End Date
June 30 2025
Last Update
April 8 2025
Active Locations (1)
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1
University of Parma - Plesso Biotecnologico Integrato
Parma, PR, Italy, 43125