Status:
RECRUITING
AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis
Lead Sponsor:
University Hospital Hradec Kralove
Collaborating Sponsors:
American Association for Thoracic Surgery
Conditions:
Systemic Inflammatory Response Syndrome
Infections
Eligibility:
All Genders
18-85 years
Brief Summary
The goal of the prospective observational study is to evaluate the immunological background of inflammatory response often seen after open thoracic aortic surgery. Patients scheduled for this type of ...
Detailed Description
It has been observed in daily clinical practice that patients after thoracic aortic replacement (of any extent, of any reason) often develop a set of specific symptoms. Those include fever, weakness a...
Eligibility Criteria
Inclusion
- Inclusion Criteria (for study group):
- patient scheduled for elective replacement of thoracic aorta of any extent by artificial vascular graft, including Bentall procedure, Yacoub procedure, supracoronary aortic replacement, also Ross procedure with supracoronary aortic replacement, hemiarch and total aortic arch replacement
- signature of informed patient consent
- Exclusion Criteria (for study group):
- active endocarditis or other infection
- unstable preoperative condition
- Inclusion Criteria (for control group):
- patient with active infectious endocarditis
- signature of informed patient consent
- Exclusion Criteria (for control group):
- more than 5 days since diagnosis
Exclusion
Key Trial Info
Start Date :
April 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06028789
Start Date
April 1 2022
End Date
June 30 2024
Last Update
May 21 2024
Active Locations (1)
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1
University Hospital Hradec Králové
Hradec Králové, Královehradecký Kraj, Czechia, 500 02