Status:
RECRUITING
Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
Lead Sponsor:
The University of Texas Health Science Center, Houston
Conditions:
Anesthesia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to assess and compare conditions for tracheal intubation obtained with modified time principal induction with 0.6 mg/kg rocuronium and 1 mg/kg succinylcholine. Specificall...
Eligibility Criteria
Inclusion
- BMI \> 30kg/m2 or Mallampati class III or IV.
- Requiring general anesthesia and endotracheal intubation
Exclusion
- Acute and chronic respiratory disorders, including Chronic obstructive pulmonary disease(COPD) and asthma.
- The American Society of Anesthesiologists (ASA) physical status classification \> III.
- Patients requiring awake intubation.
- Pregnant women.
- Untreated ischemic heart disease.
- Patients requiring an induction dose of propofol \< 1 mg/kg.
- Allergy to propofol, rocuronium, succinylcholine, or sugammadex.
- Patients with renal failure and unknown potassium (K+) level, or patients with K+ level \> 5.0
- Personal history of malignant hyperthermia (MH), or family history of MH
- Patients with suspected or diagnosed neuromuscular disease, patients with burn injuries
Key Trial Info
Start Date :
September 13 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT06029049
Start Date
September 13 2023
End Date
July 1 2025
Last Update
December 10 2024
Active Locations (1)
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1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030