Status:
COMPLETED
SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients
Lead Sponsor:
Alexandria University
Conditions:
Hyperkalemia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aims to compare the effects of Sodium Zirconium Cyclosilicate versus Sodium Polystyrene Sulfonate for treatment of hyperkalemia in patients undergoing regular hemodialysis.
Detailed Description
Patients maintained on regular hemodialysis (HD) have a high risk of hyperkalemia (\>5.0 mmol/l). Hyperkalemia is a critical medical condition that can result in arrhythmias and sudden cardiac death. ...
Eligibility Criteria
Inclusion
- ≥3 month of maintenance hemodialysis, 3 times per week for 4 hours.
- Adult patients with age above 18 years.
- baseline serum potassium level \>5 mEq/L.
Exclusion
- Gastrointestinal diseases (constipation, bleeding, Hx of endoscopy, chronic diarrhea or diarrhea in the past month, malabsorption, GIT surgery, ischemic colitis, necrosis, perforation, ….).
- Breast feeding or pregnancy.
- Patients who receive medications to treat hyperkalemia 2 weeks before study.
- myocardial infarction, acute coronary syndrome, stroke, seizure, or thromboembolic event within 8 weeks before study.
Key Trial Info
Start Date :
January 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 15 2024
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06029179
Start Date
January 15 2024
End Date
December 15 2024
Last Update
February 11 2025
Active Locations (1)
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1
Faculty of Medicine, Aexandria University
Alexandria, Egypt, 21526